When setting your Quote Expiration rules, you are able to choose whether the quote expiration timer starts ticking after the first quote is sent, or resets after the most recent quote is sent.

If you select "After the first quote is sent", your quote will expire according to the rules you've set, regardless of how many additional times you send the quote.

If you select "After the most recent quote is sent", your quote expiration timer will restart each time you send a new quote.